Identifiers
HUGO:PSEN1
HUGO:PSEN2

Identifiers

Identifiers

1. mutant PSEN@default

1. mutant PSEN@endoplasmic reticulum(ER)

1. CIB1:​mutant PSEN@endoplasmic reticulum(ER)
2. CAPN2:​mutant PSEN@endoplasmic reticulum(ER)
3. KCNIP3:​mutant PSEN@endoplasmic reticulum(ER)
4. CTNNB1:​GSK3B:​mutant PSEN@endoplasmic reticulum(ER)

1. mutant PSEN@endoplasmic reticulum(ER) → N-terminal of mutant PSEN@endoplasmic reticulum(ER) + C-terminal of mutant PSEN@endoplasmic reticulum(ER)
2. mutant PSEN@endoplasmic reticulum(ER) + APC:​AXIN:​CTNNB1:​GSK3B@neuron + APC:​AXIN:​CTNNB1:​GSK3B@neuron → CTNNB1:​GSK3B:​PRKA:​PSEN@endoplasmic reticulum(ER)
3. ER stress@endoplasmic reticulum(ER) → mutant PSEN@endoplasmic reticulum(ER)
4. mutant PSEN@endoplasmic reticulum(ER) + CAPN2@endoplasmic reticulum(ER) → CAPN2:​mutant PSEN@endoplasmic reticulum(ER)
5. mutant PSEN@endoplasmic reticulum(ER) + KCNIP3@endoplasmic reticulum(ER) → KCNIP3:​mutant PSEN@endoplasmic reticulum(ER)
6. mutant PSEN@endoplasmic reticulum(ER) + CIB1@neuron → CIB1:​mutant PSEN@endoplasmic reticulum(ER)

1. IP3@neuron + ITPR@endoplasmic reticulum(ER) → IP3:​ITPR@endoplasmic reticulum(ER)
2. APP@neuron → sAPPB@default + C99@default
3. MAPT |​Hypophosphorylated@neuron → MAPT|​pho@neuron
4. APP@endoplasmic reticulum(ER) → AmyloidB|​hm10@neuron + unknown@endoplasmic reticulum(ER)
5. EIF2AK3@endoplasmic reticulum(ER) → EIF2AK3|​pho|​active@endoplasmic reticulum(ER)
6. ATF6@endoplasmic reticulum(ER) → ATF6@endoplasmic reticulum(ER)
7. ERN1@endoplasmic reticulum(ER) → ERN1|​pho|​hm2|​active@endoplasmic reticulum(ER)
8. RYR3@endoplasmic reticulum(ER) → RYR3@endoplasmic reticulum(ER)
9. XBP1@endoplasmic reticulum(ER) → XBP1@endoplasmic reticulum(ER)