Reaction state_transition re3

(ErbB1_br_ligand|​hm2:​active_br_EGFR|​hm2)|​active@default + ATP@default → (ErbB1_br_ligand|​hm2:​active_br_EGFR|​Y992_pho|​Y1045_pho|​Y1068_pho|​Y1086_pho|​Y1148_pho|​Y1173_pho|​hm2)|​active@default + ADP@default

Reaction regulators:

Catalysis

1. (ErbB1_br_ligand|​hm2:​active_br_EGFR|​hm2)|​active@default

Inhibition

1. KDI1@default

autophosphorylation: PMID:10880430 PMID:11252954 PMID:7834741 PMID:9708728 PMID:6090945 PMID:2543678 PMID:1688559
conformational change: PMID:10069801
KDI1: PMID:12842895