Complex ErbB1_br_ligand:active_br_EGFR
Complex composition:
- ErbB1_br_ligand
- active_br_EGFR
(ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
PMID:9667855 PMID:9779993
Modifications:
Participates in complexes:
In compartment: default
- (ErbB1_br_ligand|hm2:active_br_EGFR|hm2)|active@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y845_pho|Y891_pho|Y920_pho|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1101_pho|Y1148_pho|Y1173_pho|hm2)|active@default
Participates in reactions:
As Reactant or Product:- EGFR:ErbB1_br_ligand@default
+ EGFR:ErbB1_br_ligand@default
→
(ErbB1_br_ligand|hm2:active_br_EGFR|hm2)|active@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y845_pho|Y891_pho|Y920_pho|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1101_pho|Y1148_pho|Y1173_pho|hm2)|active@default
→
mitogenesis@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y845_pho|Y891_pho|Y920_pho|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1101_pho|Y1148_pho|Y1173_pho|hm2)|active@default
→
tumorigenesis@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y845_pho|Y891_pho|Y920_pho|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1101_pho|Y1148_pho|Y1173_pho|hm2)|active@default
→
(ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|hm2)|active@default
+ ATP@default
→
(ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
+ ADP@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
→
(ErbB1_br_ligand|hm2:active_br_EGFR|Y845_pho|Y891_pho|Y920_pho|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1101_pho|Y1148_pho|Y1173_pho|hm2)|active@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
→
(ErbB1_br_ligand|hm2:active_br_EGFR|hm2)|active@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
→
(ErbB1_br_ligand|hm2:early end._br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@early_br_endsome
As Catalyser:- SHP1@default
→
SHP1_br_@EGFR._br_Y1173P@default
- SHP2@default
→
SHP2_br_@EGFR.@default
- Eps8@default
→
Eps8_br_@EGFR.|Y_pho@default
- Vav2@default
→
Vav2_br_@EGFR._br_Y992/1148P@default
- RasGAP@default
→
RasGAP_br_@EGFR._br_Y992P@default
- Gab1@default
→
Gab1@EGFR._br_Y1068/1086P|Y446_pho|Y472_pho|Y589_pho@default
- Grb2_br_@EGFR._br_Y1068/1086P@default
+ Gab1@default
→
Gab1|Y446_pho|Y472_pho|Y589_pho:Grb2_br_@EGFR._br_Y1068/1086P@default
- PLC_gamma@default
→
PLC_gamma__br_@EGFR._br_Y992/1173P|Y472_pho|Y771_pho|Y783_pho|Y1254_pho|active@default
- STAT1@default
→
STAT1|Y701_pho@default
- STAT3@default
→
STAT3|Y705_pho@default
- (ErbB1_br_ligand|hm2:active_br_EGFR|hm2)|active@default
+ ATP@default
→
(ErbB1_br_ligand|hm2:active_br_EGFR|Y992_pho|Y1045_pho|Y1068_pho|Y1086_pho|Y1148_pho|Y1173_pho|hm2)|active@default
+ ADP@default
- Shc@default
→
Shc_br_@EGFR._br_Y1148/1173P|Y317_pho@default
- Grb2@default
→
Grb2_br_@EGFR._br_Y1068/1086P@default
- Grb2:SOS1@default
→
Grb2_br_@EGFR._br_Y1068/1086P:active_br_SOS1@default