Protein IRAK1 map

Identifiers
HUGO:IRAK1

Maps_Modules
 MACROPHAGE  map
MODULE:CORE_SIGNALING_PATHWAYS
MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS
CASCADE:TLR2_4
CASCADE:IL18

References
PMID:12620219
MyD88 mediates a close interaction of the two related IRAK molecules,
which is essential to allow IRAK-4 to phosphorylate IRAK-1. Phosphorylation of IRAK-1
reduces its affinity for MyD88, while increasing its affinity for TRAF6.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. IRAK1@INNATE_IMMUNE_CELL_Cytosol map
  2. IRAK1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. IRAK1@INNATE_IMMUNE_CELL_Cytosol map → map IRAK1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. TRAF6@INNATE_IMMUNE_CELL_Cytosol map → map TRAF6@INNATE_IMMUNE_CELL_Cytosol map