Simple molecule H_sub_2_endsub_O_sub_2_endsub_ map
H_sub_2_endsub_O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane

Maps_Modules
 DENDRITIC_CELL  map
MODULE:IMMUNE_STIMULATION
CHEBI:16240, KEGGCOMPOUND:C00027, CAS:7722-84-1
MODULE:ANTIGEN_PRESENTATION
MODULE:EFFECTOR_ACTIVATION

H_sub_2_endsub_O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol

Maps_Modules
 MACROPHAGE  map
 NEUTROPHIL  map
MODULE:TUMOR_KILLING
MODULE:EFFECTOR_ACTIVATION
MODULE:NO_ROS_PRODUCTION
CASCADE:TGFB

References
PMID:19732719
Inhibition of TGF-ß signaling in vivo increases CD11b+ cell cytotoxicity via an oxygen radical-dependent mechanism (superoxide  and H2O2 production) in neutrophils
PMID:24092389
TANs from early tumors are more cytotoxic toward tumor cells and produce higher levels of TNF-α, NO, and H2O2 and, in established tumors, these functions are downregulated and TAN acquire a more protumorigenic phenotype

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. H_sub_2_endsub_O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map
In compartment: PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
  1. H_sub_2_endsub_O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. O_sub_2_endsub__super_-_endsuper_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map H_sub_2_endsub_O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
    2. H_sub_2_endsub_O_sub_2_endsub_@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map hydroxyl@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map
    3. O_sub_2_endsub__super_-_endsuper_@INNATE_IMMUNE_CELL_Cytosol map → map H_sub_2_endsub_O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map
    4. H_sub_2_endsub_O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map → map hydroxyl@INNATE_IMMUNE_CELL_Cytosol map
    5. H_sub_2_endsub_O_sub_2_endsub_@INNATE_IMMUNE_CELL_Cytosol map → map ROS_production@default map
    As Catalyser:
    1. gMIF@INNATE_IMMUNE_CELL_Cytosol map → map rMIF@INNATE_IMMUNE_CELL_Cytosol map
    2. Tumor_antigen@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map → map Tumor_antigen_fragment@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map