Protein LIMK1 map

Identifiers
HUGO:LIMK1

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
 NATURAL_KILLER  map
PMID:11698448
LIMK1 is a serine/threonine kinase that phosphorylates and inactivates the actin-depolymerization factor cofilin, thereby regulating actin cytoskeletal reorganization.
FcR-initiated LIMK1 phosphorylation was absent in the NK clones that had been treated with p160ROCK kinase inhibitor.
Inhibition of the RhoA/p160ROCK/LIMK1 signaling pathway abrogates lipid raft polarization to the effector-target interface

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. LIMK1@INNATE_IMMUNE_CELL_Cytosol map
  2. LIMK1|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. LIMK1@INNATE_IMMUNE_CELL_Cytosol map → map LIMK1|​pho@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. CFL1@INNATE_IMMUNE_CELL_Cytosol map → map CFL1|​pho@INNATE_IMMUNE_CELL_Cytosol map