Gene TNIP3 map

Identifiers
HUGO:TNIP3

Maps_Modules
 MACROPHAGE  map
MODULE:CORE_SIGNALING_PATHWAYS
MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS
CASCADE:IL10

References
PMID:17485448
IL10 upregulates expression of TNIP3 (ABIN3)
TNIP3 (ABIN3‭) ‬inhibits IKK complex trough direct binding to IKBKG.
It results in inhibition of‭ ‬FNKBIA phosphorylation and
proteasomal degradation and prevents activation
of downstream‭ ‬NFkB‭ ‬signaling‭ ‬downstream of IL10.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gTNIP3@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gTNIP3@INNATE_IMMUNE_CELL_Cytosol map → map rTNIP3@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: