Complex WASP*:WIPF1 map
Complex composition:

  1. WIPF1 map
  2. WASP* map

WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:WASP*:WIPF1

Maps_Modules
MODULE:TUMOR_KILLING MODULE:EFFECTOR_ACTIVATION MODULE:EXOCYTOSIS_AND_PHAGOCYTOSIS

References
CASCADE:KIR2DL1
16606694
Protein kinase C-theta mediates phosphorylation of WIPF1 downstream of NK activation. Inhibitory signaling from KIR2DL1 receptor.
Phosphorylated WIPF1 provides recruitment of of F-actin and MYH9 (myosin IIA) to multiprotein WASP :WIPF1 complexs.
17890224
in macrophages WASP and WASP-interacting protein (WIP) form a complex at the phagocytic cup and that the WASP.WIP complex plays a critical role in the phagocytic cup formation.

WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:WASP*:WIPF1

Maps_Modules
MODULE:TUMOR_KILLING MODULE:EFFECTOR_ACTIVATION MODULE:EXOCYTOSIS_AND_PHAGOCYTOSIS

References
 NATURAL_KILLER  map
CASCADE:KIR2DL1
PMID:16606694
WIPF1 forms complex with WASP. Protein kinase C-theta mediates phosphorylation of WIPF1 downstream of NK activation. Inhibitory signaling from KIR2DL1 receptor

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol map
  2. WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho@INNATE_IMMUNE_CELL_Cytosol map + WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map → map ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  2. WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol map → map WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. WASP*|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map + WIPF1@INNATE_IMMUNE_CELL_Cytosol map → map WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: