Complex IL15:IL15RA map
Complex composition:

  1. IL15RA map
  2. IL15 map

IL15:​IL15RA@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:IL15:IL15RA

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:IMMUNE_STIMULATION MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
CASCADE:IL15
PMID:17398124, PMID:19913445, PMID:17459805, PMID:21307131
Dendritic cells and macrophages prime natural killer cells by trans-presenting interleukin 15.
IL-15 is trans-presented on the surface of IL-15-producing cells in complex with the IL-15 receptor α chain (IL-15Rα).
It results in tumoricidal activity of NK cells.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. IL15:​IL15RA@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL15@INNATE_IMMUNE_CELL_Cytosol map + IL15RA@INNATE_IMMUNE_CELL_Membrane map → map IL15:​IL15RA@INNATE_IMMUNE_CELL_Membrane map
As Catalyser: