Protein ETS1
Identifiers
HUGO:ETS1
Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:MIRNA_TF_IMMUNOSTIMULATORY
References
NATURAL_KILLER
CASCADE:IL15
CASCADE:IL2
PMID:22608498
ETS1 binds directly to the Tbx21 and IL2RB (CD122) genes and induces its expression in NK cells.
expression of Ncr1 (NKp46), Cd122 (il2RB), Idb2, Ltb, Lair1 and Tbx21 mRNA is reduced in NK cells after knockdown of ETS1.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- ETS1@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- rETS1@INNATE_IMMUNE_CELL_Cytosol
→
ETS1@INNATE_IMMUNE_CELL_Cytosol
As Catalyser:- gTBX21@INNATE_IMMUNE_CELL_Cytosol
→
rTBX21@INNATE_IMMUNE_CELL_Cytosol
- gIL2RB@INNATE_IMMUNE_CELL_Cytosol
→
rIL2RB@INNATE_IMMUNE_CELL_Cytosol
- gLTB@INNATE_IMMUNE_CELL_Cytosol
→
rLTB@INNATE_IMMUNE_CELL_Cytosol
- gNKp46*@INNATE_IMMUNE_CELL_Cytosol
→
rNKp46*@INNATE_IMMUNE_CELL_Cytosol