Complex S1PR*:Sphingosine 1-phosphate
Complex composition:
- S1PR*
- Sphingosine 1-phosphate
S1PR*:Sphingosine 1-phosphate@INNATE_IMMUNE_CELL_Membrane
Identifiers
NAME:S1PR*:Sphingosine 1-phosphate
Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:DANGER_SIGNAL_PATHWAYS MODULE:RECRUITMENT_OF_IMMUNE_CELLS
References
DENDRITIC_CELL
CASCADE:S1PR
PMID:11919175
S1P induces Ca2+ mobilization, actin polymerization, and migration
in immature, but not in LPS-differentiated DC. S1P reduces IL-12 and TNF-α production,
and augments IL-10 release in maturing DC inhibiting their capacity to induce Th1 immune responses.
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
- S1PR*:Sphingosine 1-phosphate@INNATE_IMMUNE_CELL_Membrane
Participates in reactions:
As Reactant or Product:- S1PR*:Sphingosine 1-phosphate@INNATE_IMMUNE_CELL_Membrane
→
RECRUITMENT_OF_IMMUNE_CELLS@INNATE_IMMUNE_CELL_Cytosol
- Sphingosine 1-phosphate@TUMOR_CELL_AS_INDUCTOR
+ S1PR*@INNATE_IMMUNE_CELL_Membrane
→
S1PR*:Sphingosine 1-phosphate@INNATE_IMMUNE_CELL_Membrane
As Catalyser: