Protein IP3R* map

Identifiers
HUGO:ITPR1 HGNC:6180 ENTREZ:3708 UNIPROT:Q14643 GENECARDS:ITPR1 HUGO:ITPR2 HGNC:6181 ENTREZ:3709 UNIPROT:Q14571 GENECARDS:ITPR2 HUGO:ITPR3 HGNC:6182 ENTREZ:3710 UNIPROT:Q14573 GENECARDS:ITPR3

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
REACTOME:405731 KEGG:3708 ATLASONC:GC_ITPR1 WIKI:ITPR1
REACTOME:405722 KEGG:3709 ATLASONC:GC_ITPR2 WIKI:ITPR2
REACTOME:57433 KEGG:3710 ATLASONC:GC_ITPR3 WIKI:ITPR3
PMID:7890616
PCL (probably PCLG1) induces hydrolysis of phosphoinositides and activates InsP3-induced intracellular Ca2+ release downstream of IL13.

Modifications:
In compartment: Endoplasmic Reticulum
  1. IP3R*@Endoplasmic Reticulum map
Participates in complexes:
In compartment: Endoplasmic Reticulum
  1. IP3:​IP3R*@Endoplasmic Reticulum map
Participates in reactions:
As Reactant or Product:
  1. IP3@INNATE_IMMUNE_CELL_Cytosol map + IP3R*@Endoplasmic Reticulum map → map IP3:​IP3R*@Endoplasmic Reticulum map
As Catalyser:
  1. Ca2+@Endoplasmic Reticulum map → map Ca2+@INNATE_IMMUNE_CELL_Cytosol map