Identifiers
HUGO:MMP9
Maps_Modules
MACROPHAGE
MDSC
MODULE:EFFECTOR_INHIBITION
MODULE:TUMOR_GROWTH
MODULE:MATRIX_REMODELLING
CASCADE:MIF
CASCADE:IL10
CASCADE:IL4
CASCADE:IFNAB
NEUTROPHIL
References
PMID:11875494
MMPs plays important in the degradation and remodeling of the
extracellular matrix at sites of inflammation. HMOX1 (HO1) mediates IL-10-induced suppression
of MMP9 expression.
PMID:23390297, PMID:22461508
MIF signaling induces angiogenesis probavly via upregulation of MMP9, VEGF expression in macrophages and activates tumor invasion