Protein SP1 map

Identifiers
HUGO:SP1

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:MIRNA_TF_IMMUNOSTIMULATORY

References
 NATURAL_KILLER  map
CASCADE:IL12
PMID:17705132
SP1 directly activate TBX21 (T-Bet) promoter in NK cells downstream of IL12, IL15.
Mithramycin A inhibits while monokines increase Sp1 binding to T-BET promoter and
downregulates T-BET and IFNG expression in NK cells.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. SP1@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. SP1@INNATE_IMMUNE_CELL_Cytosol map → map SP1@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. gTBX21@INNATE_IMMUNE_CELL_Cytosol map → map rTBX21@INNATE_IMMUNE_CELL_Cytosol map