Protein FLT1 map

Identifiers
HUGO:FLT1

Maps_Modules
MODULE:MARKERS_MDSC MODULE:INPUT_INHIBITORS MODULE:IMMUNE_SUPPRESSION MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS

References
 DENDRITIC_CELL  map
 MDSC  map
CASCADE:VEGFA
PMID:16002046, PMID:9570538
Inhibitory function of VEGF on DC function is most likely mediated by Flt-1.
PMID:16002046
Id1−/− DCs did not respond to the VEGF stimulus because of defective Flt-1 signaling in these mutant mice. Thus, Flt-1 seems to be an important player in VEGF–DC interactions.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. FLT1@INNATE_IMMUNE_CELL_Membrane map
In compartment: MARKERS_MDSC
  1. FLT1@MARKERS_MDSC map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. FLT1:​VEGFA@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. VEGFA@default map + FLT1@INNATE_IMMUNE_CELL_Membrane map → map FLT1:​VEGFA@INNATE_IMMUNE_CELL_Membrane map
  2. rFLT1@INNATE_IMMUNE_CELL_Cytosol map → map FLT1@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. ID1@INNATE_IMMUNE_CELL_Cytosol map → map ID1@INNATE_IMMUNE_CELL_Cytosol map