Identifiers
HUGO:SMAD2
Maps_Modules
MODULE:INPUT_INHIBITORS MODULE:IMMUNE_SUPPRESSION MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
References
CASCADE:TGFB
CASCADE:IL12
CASCADE:IL18
PMID:16713975
SMAD2, SMAD3 and SMAD4 participate in suppression of TBX21 (T-BET) promoter activity downstream of TGFB.
costimulation of NK cells with IL-12 and IL-18 downregulated SMAD2 transcript.