Protein MAP2K3 map

Identifiers
HUGO:MAP2K3

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
CASCADE:INTEGRIN_A4B1
CASCADE:INTEGRIN_A5B1
CASCADE:TLR2_4
PMID:10661401
MKK3 is activated by β1 Integrin Cross-Linking on Human NK Cells,
It activates p38MAPK regulated IL8 production by NK cells downstream of integrin signaling.
PMID:9379049
MKK3 and MKK4 are capable of phosphorylating p38mapk in macrophages,
downstream of TNF/Tnf receptor signaling.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MAP2K3@INNATE_IMMUNE_CELL_Cytosol map
  2. MAP2K3|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. MAP2K3@INNATE_IMMUNE_CELL_Cytosol map → map MAP2K3|​pho@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. p38*@INNATE_IMMUNE_CELL_Cytosol map → map p38*|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map