Protein EIF4E map

Identifiers
HUGO:EIF4E

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
 NATURAL_KILLER  map
PMID:15563472
Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells.
Phosphorylation by MNK1 serves to activate eIF4E.eIF4E induces translation of ETS1by recruiting mRNAs to the ribosome,
and upregulates ETS1 protein level.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. EIF4E@INNATE_IMMUNE_CELL_Cytosol map
  2. EIF4E|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. EIF4E@INNATE_IMMUNE_CELL_Cytosol map → map EIF4E|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. rETS1@INNATE_IMMUNE_CELL_Cytosol map → map ETS1@INNATE_IMMUNE_CELL_Cytosol map