Complex CYBA:CYBB:NCF1:NCF2:NCF4:RAC1:RAC2 map
Complex composition:

  1. NCF4 map
  2. NCF1 map
  3. CYBA map
  4. NCF2 map
  5. CYBB map
  6. RAC2 map
  7. RAC1 map

(CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@microglia
Symbol:
Name: NADPH oxidase complex
Description:
Previous Symbols:
Synonyms:
A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
(CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@phagolysosome
Symbol:
Name: NADPH oxidase complex
Description:
Previous Symbols:
Synonyms:
A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
Modifications:
Participates in complexes:
In compartment: microglia
  1. (CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@microglia map
In compartment: phagolysosome
  1. (CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@phagolysosome map
Participates in reactions:
As Reactant or Product:
  1. Apocynin@default map → map (CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@microglia map
  2. (CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@phagolysosome map → map ROS@phagolysosome map
  3. rotenone@microglia map → map (CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@microglia map
  4. CYBA:​CYBB@microglia map + NCF1:​NCF2:​NCF4@microglia map + RAC1|​GTP@microglia map + RAC2|​GTP@microglia map → map (CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@microglia map
As Catalyser:
  1. NADPH@microglia map → map NADP_plus_@microglia map
  2. O2@default map → map superoxide@default map