Simple molecule ROS
Modifications:
In compartment: default
- ROS@default
In compartment: microglia
- ROS@microglia
In compartment: mitochondrial matrix
- ROS@mitochondrial matrix
In compartment: mitochondrion
- ROS@mitochondrion
In compartment: neuron
- ROS@neuron
In compartment: nucleus
- ROS@nucleus
In compartment: phagolysosome
- ROS@phagolysosome
Participates in complexes:
Participates in reactions:
As Reactant or Product:- Ca2+@mitochondrial matrix
→
ROS@mitochondrial matrix
- SNCA@mitochondrial matrix
→
ROS@neuron
- SNCA|mutated A53T@mitochondrial matrix
→
ROS@neuron
- DOPAL@neuron
→
ROS@neuron
- ROS@mitochondrial matrix
→
mitochondrial depolarization@mitochondrion
- ROS@neuron
→
DAPK1@neuron
- superoxide@mitochondrial matrix
→
ROS@mitochondrial matrix
- hydroxyl@mitochondrial matrix
→
ROS@mitochondrial matrix
- ROS@mitochondrion
→
PINK1@mitochondrion
- ROS@mitochondrion
→
mt UPR@mitochondrion
- ROS@neuron
→
ATF4@neuron
- hydrogen peroxide@mitochondrial matrix
→
ROS@mitochondrial matrix
- superoxide@mitochondrial matrix
→
ROS@mitochondrial matrix
- ROS@neuron
→
MAP3K5@neuron
- ROS@default
→
(IGF1R:IRS1)|active@neuron
- tetrahydrobiopterin@neuron
→
ROS@neuron
- ROS@microglia
→
NFkB cascade@microglia
- ROS@phagolysosome
→
ROS@microglia
- ROS@microglia
→
NFE2L2 cascade@microglia
- PTGS2@microglia
→
ROS@microglia
- (CYBA:CYBB:NCF1|pho:NCF2|pho:NCF4:RAC1|GTP:RAC2|GTP)|active@phagolysosome
→
ROS@phagolysosome
- ROS@microglia
→
MAPK cascade@microglia
- ROS@microglia
→
NFE2L2 cascade@microglia
- ROS@mitochondrial matrix
→
generic protein|oxidized@mitochondrial matrix
- mitochondrial dysfunction@mitochondrial matrix
→
ROS@mitochondrial matrix
As Catalyser:- CHUK:IKBKB:IKBKG@neuron
→
(CHUK:IKBKB|S176_pho|S180_pho:IKBKG)|active@neuron
- PPIF:SLC25A4:VDAC1@mitochondrial matrix
→
PPIF:SLC25A4:VDAC1@mitochondrial matrix
- ATXN3@neuron
→
ATXN3@nucleus
- (CUL3:KEAP1)|active@neuron
→
CUL3:KEAP1|oxidized cysteine@neuron
- SNCA|S129_pho@neuron
→
s10184
- s10184 →
s3418
- GSTP1@neuron
+ MAPK8@neuron
→
GSTP1:MAPK8@neuron
- glutathione@neuron
+ PSMA5@neuron
→
PSMA5|S-glutathione@neuron
- (KCNJ11:KCNJ8)|active@mitochondrial matrix
→
(KCNJ11:KCNJ8)|active@mitochondrial matrix
- PARK7@neuron
→
PARK7|active|SOH@C106@neuron
- HTRA2@mitochondrion
→
HTRA2|S400_pho|hm3|active@mitochondrion
- PINK1@mitochondrion
+ PARK2|ubi|active@neuron
→
PARK2:PINK1@mitochondrion
- MEF2C@nucleus
→
MEF2C|SOH@nucleus
- SIRT3@mitochondrial matrix
→
SIRT3@mitochondrial matrix
- SNCA@neuron
→
SNCA@nucleus
- TXN:TXNIP@microglia
→
TXN|oxidized@microglia
+ TXNIP@microglia
- L_minus_glutamate@default
→
L_minus_glutamate@astrocyte
- DNM1L@mitochondrion
+ VPS35@neuron
→
DNM1L:VPS35@oxidized lipid membrane
- MAP3K5:TXN@neuron
→
TXN|oxidized@neuron
+ MAP3K5@neuron
- SNCA@neuron
→
s10184