Simple molecule ROS  
 
Modifications:
In compartment: default
- ROS@default 
 
 
In compartment: microglia
- ROS@microglia 
 
 
In compartment: mitochondrial matrix
- ROS@mitochondrial matrix 
 
 
In compartment: mitochondrion
- ROS@mitochondrion 
 
 
In compartment: neuron
- ROS@neuron 
 
 
In compartment: nucleus
- ROS@nucleus 
 
 
In compartment: phagolysosome
- ROS@phagolysosome 
 
 
Participates in complexes:
Participates in reactions:
As Reactant or Product:- Ca2+@mitochondrial matrix 
  → 
  ROS@mitochondrial matrix 
 
 - SNCA@mitochondrial matrix 
  → 
  ROS@neuron 
 
 - SNCA|mutated A53T@mitochondrial matrix 
  → 
  ROS@neuron 
 
 - DOPAL@neuron 
  → 
  ROS@neuron 
 
 - ROS@mitochondrial matrix 
  → 
  mitochondrial depolarization@mitochondrion 
 
 - ROS@neuron 
  → 
  DAPK1@neuron 
 
 - superoxide@mitochondrial matrix 
  → 
  ROS@mitochondrial matrix 
 
 - hydroxyl@mitochondrial matrix 
  → 
  ROS@mitochondrial matrix 
 
 - ROS@mitochondrion 
  → 
  PINK1@mitochondrion 
 
 - ROS@mitochondrion 
  → 
  mt UPR@mitochondrion 
 
 - ROS@neuron 
  → 
  ATF4@neuron 
 
 - hydrogen peroxide@mitochondrial matrix 
  → 
  ROS@mitochondrial matrix 
 
 - superoxide@mitochondrial matrix 
  → 
  ROS@mitochondrial matrix 
 
 - ROS@neuron 
  → 
  MAP3K5@neuron 
 
 - ROS@default 
  → 
  (IGF1R:IRS1)|active@neuron 
 
 - tetrahydrobiopterin@neuron 
  → 
  ROS@neuron 
 
 - ROS@microglia 
  → 
  NFkB cascade@microglia 
 
 - ROS@phagolysosome 
  → 
  ROS@microglia 
 
 - ROS@microglia 
  → 
  NFE2L2 cascade@microglia 
 
 - PTGS2@microglia 
  → 
  ROS@microglia 
 
 - (CYBA:CYBB:NCF1|pho:NCF2|pho:NCF4:RAC1|GTP:RAC2|GTP)|active@phagolysosome 
  → 
  ROS@phagolysosome 
 
 - ROS@microglia 
  → 
  MAPK cascade@microglia 
 
 - ROS@microglia 
  → 
  NFE2L2 cascade@microglia 
 
 - ROS@mitochondrial matrix 
  → 
  generic protein|oxidized@mitochondrial matrix 
 
 - mitochondrial dysfunction@mitochondrial matrix 
  → 
  ROS@mitochondrial matrix 
 
 
As Catalyser:- CHUK:IKBKB:IKBKG@neuron 
  → 
  (CHUK:IKBKB|S176_pho|S180_pho:IKBKG)|active@neuron 
 
 - PPIF:SLC25A4:VDAC1@mitochondrial matrix 
  → 
  PPIF:SLC25A4:VDAC1@mitochondrial matrix 
 
 - ATXN3@neuron 
  → 
  ATXN3@nucleus 
 
 - (CUL3:KEAP1)|active@neuron 
  → 
  CUL3:KEAP1|oxidized cysteine@neuron 
 
 - SNCA|S129_pho@neuron 
  → 
  s10184
 - s10184 → 
  s3418
 - GSTP1@neuron 
  + MAPK8@neuron 
  → 
  GSTP1:MAPK8@neuron 
 
 - glutathione@neuron 
  + PSMA5@neuron 
  → 
  PSMA5|S-glutathione@neuron 
 
 - (KCNJ11:KCNJ8)|active@mitochondrial matrix 
  → 
  (KCNJ11:KCNJ8)|active@mitochondrial matrix 
 
 - PARK7@neuron 
  → 
  PARK7|active|SOH@C106@neuron 
 
 - HTRA2@mitochondrion 
  → 
  HTRA2|S400_pho|hm3|active@mitochondrion 
 
 - PINK1@mitochondrion 
  + PARK2|ubi|active@neuron 
  → 
  PARK2:PINK1@mitochondrion 
 
 - MEF2C@nucleus 
  → 
  MEF2C|SOH@nucleus 
 
 - SIRT3@mitochondrial matrix 
  → 
  SIRT3@mitochondrial matrix 
 
 - SNCA@neuron 
  → 
  SNCA@nucleus 
 
 - TXN:TXNIP@microglia 
  → 
  TXN|oxidized@microglia 
  + TXNIP@microglia 
 
 - L_minus_glutamate@default 
  → 
  L_minus_glutamate@astrocyte 
 
 - DNM1L@mitochondrion 
  + VPS35@neuron 
  → 
  DNM1L:VPS35@oxidized lipid membrane 
 
 - MAP3K5:TXN@neuron 
  → 
  TXN|oxidized@neuron 
  + MAP3K5@neuron 
 
 - SNCA@neuron 
  → 
  s10184