Reaction state_transition re3987 
 
HTRA2@mitochondrion 
  → HTRA2|S400_pho|hm3|active@mitochondrion 
 
Reaction regulators:
- Catalysis
 - ROS@mitochondrion 
  - CDK5@mitochondrion 
  - MAPK14|T180_pho|Y182_pho|active@mitochondrion 
  - MAPK12@mitochondrion 
  
- Modulation
 - PINK1@mitochondrion