Protein PINK1  
 
Modifications:
In compartment: Lewy body
- PINK1@Lewy body 
 
 
In compartment: dendritic shaft
- PINK1@dendritic shaft 
 
 
In compartment: mitochondrial matrix
- PINK1@mitochondrial matrix 
 
 - PINK1@mitochondrial matrix 
 
 
In compartment: mitochondrion
- PINK1@mitochondrion 
 
 - PINK1@mitochondrion 
 
 
In compartment: neuron
- PINK1@neuron 
 
 
Participates in complexes:
In compartment: mitochondrion
- PARK2:PINK1@mitochondrion 
 
 - BCL2L1:PINK1@mitochondrion 
 
 - PINK1:nuclear RCC RNA@mitochondrion 
 
 
In compartment: neuron
- BECN1:PINK1@neuron 
 
 
Participates in reactions:
As Reactant or Product:- PINK1@neuron 
  → 
  PINK1@mitochondrion 
 
 - PINK1@mitochondrion 
  → 
  PINK1@mitochondrial matrix 
 
 - PINK1@mitochondrial matrix 
  → 
  PINK1 (fragment 52kD)@mitochondrion 
 
 - PINK1@mitochondrion 
  → 
  PINK1@mitochondrion 
 
 - PARK2:PINK1@mitochondrion 
  → 
  mitophagy@neuron 
 
 - NEDD8@neuron 
  → 
  PINK1@neuron 
 
 - MARK2@neuron 
  → 
  PINK1@mitochondrion 
 
 - PINK1@neuron 
  → 
  TRAF2:TRAF6@neuron 
 
 - PINK1@neuron 
  → 
  MAP3K7@neuron 
 
 - PARK2@neuron 
  + PINK1@mitochondrion 
  → 
  PARK2:PINK1@mitochondrion 
 
 - PINK1@neuron 
  → 
  ubiquitin|S65_pho@neuron 
 
 - ROS@mitochondrion 
  → 
  PINK1@mitochondrion 
 
 - PINK1@mitochondrial matrix 
  → 
  degraded
 - BECN1@neuron 
  + PINK1@neuron 
  → 
  BECN1:PINK1@neuron 
 
 - BECN1:PINK1@neuron 
  → 
  BECN1:PIK3C3:PIK3R4@neuron 
 
 - PINK1@dendritic shaft 
  → 
  dendrite extension@dendritic shaft 
 
 - PINK1@dendritic shaft 
  → 
  mitochondrial motility@dendritic shaft 
 
 - PINK1@dendritic shaft 
  → 
  s8071
 - PINK1@dendritic shaft 
  → 
  MAP2@dendritic shaft 
 
 - PINK1@mitochondrion 
  + PARK2|ubi|active@neuron 
  → 
  PARK2:PINK1@mitochondrion 
 
 - PINK1@neuron 
  → 
  PINK1@neuron 
 
 - PINK1@neuron 
  → 
  degraded
 - BCL2L1@neuron 
  + PINK1@mitochondrion 
  → 
  BCL2L1:PINK1@mitochondrion 
 
 - BCL2L1:PINK1@mitochondrion 
  → 
  BCL2L1|S62_pho@neuron 
 
 - SREBF1@neuron 
  → 
  PINK1@mitochondrion 
 
 - TOMM20:TOMM22:TOMM40:TOMM5:TOMM6:TOMM7:TOMM70@mitochondrion 
  → 
  PINK1@mitochondrion 
 
 - PINK1@mitochondrion 
  + PARK2|ubi|active@neuron 
  → 
  PARK2:PINK1@mitochondrion 
 
 - PINK1:nuclear RCC RNA@mitochondrion 
  → 
  s8616
 - PUM1:nuclear RCC RNA@mitochondrion 
  + PINK1@neuron 
  → 
  PINK1:nuclear RCC RNA@mitochondrion 
  + PUM1@neuron 
 
 - PINK1@neuron 
  → 
  SIRT1@neuron 
 
 - PINK1@mitochondrion 
  → 
  s10479
 - VPS13C@mitochondrion 
  → 
  PARK2:PINK1@mitochondrion 
 
 - PINK1@mitochondrion 
  + PARK2|ubi|active@neuron 
  → 
  PARK2:PINK1@mitochondrion 
 
 - PINK1@mitochondrion 
  → 
  PARK2|ubi|active@neuron 
 
 - chaperone-mediated protein folding@mitochondrion 
  → 
  PINK1@mitochondrion 
 
 
As Catalyser:- TOMM20:TOMM22:TOMM40:TOMM5:TOMM6:TOMM7:TOMM70@mitochondrion 
  → 
  TOMM40|ubi@neuron 
  + TOMM20|ubi@neuron 
  + TOMM70@neuron 
 
 - PARK2@neuron 
  → 
  PARK2|ubi|active@neuron 
 
 - VDAC1@mitochondrion 
  → 
  VDAC1|ubi@mitochondrion 
 
 - MFN1@mitochondrion 
  → 
  MFN1|ubi@neuron 
 
 - MFN2@mitochondrion 
  → 
  MFN2|ubi@neuron 
 
 - HDAC6@neuron 
  → 
  HDAC6@mitochondrion 
 
 - FIS1@mitochondrion 
  → 
  FIS1|ubi@mitochondrion 
 
 - TRAP1@mitochondrion 
  → 
  TRAP1|pho@mitochondrion 
 
 - HTRA2@mitochondrion 
  → 
  HTRA2|S400_pho|hm3|active@mitochondrion 
 
 - DNM1L@neuron 
  → 
  DNM1L|S637_pho@neuron 
 
 - RHOT1@mitochondrion 
  → 
  RHOT1|pho|ubi@neuron 
 
 - RHOT2@mitochondrion 
  → 
  RHOT2|pho|ubi@neuron 
 
 - PRKAR2B@Striatal Projection Neuron 
  → 
  PRKAR2B|pho@dendritic shaft 
 
 - HNRNPF:PUM1:nuclear RCC RNA@neuron 
  → 
  PUM1:nuclear RCC RNA@neuron 
  + HNRNPF@neuron 
 
 - PUM1:nuclear RCC RNA@neuron 
  → 
  PUM1:nuclear RCC RNA@mitochondrion 
 
 - s8645 → 
  s11040
 - NDUFA10@mitochondrion 
  → 
  (Fe-S protein:MT-ND1:MT-ND2:MT-ND3:MT-ND4:MT-ND4L:MT-ND5:MT-ND6:NDUFAB1:NDUFAF1:NDUFC1:NDUFC2:NDUFV1:NDUFV2:NDUFV3:alpha subcomplex:beta subcomplex)|active@mitochondrial matrix 
 
 - generic protein|oxidized@mitochondrial matrix 
  → 
  generic protein|oxidized@oxidized lipid membrane