Protein PINK1
Modifications:
In compartment: Lewy body
- PINK1@Lewy body
In compartment: dendritic shaft
- PINK1@dendritic shaft
In compartment: mitochondrial matrix
- PINK1@mitochondrial matrix
- PINK1@mitochondrial matrix
In compartment: mitochondrion
- PINK1@mitochondrion
- PINK1@mitochondrion
In compartment: neuron
- PINK1@neuron
Participates in complexes:
In compartment: mitochondrion
- PARK2:PINK1@mitochondrion
- BCL2L1:PINK1@mitochondrion
- PINK1:nuclear RCC RNA@mitochondrion
In compartment: neuron
- BECN1:PINK1@neuron
Participates in reactions:
As Reactant or Product:- PINK1@neuron
→
PINK1@mitochondrion
- PINK1@mitochondrion
→
PINK1@mitochondrial matrix
- PINK1@mitochondrial matrix
→
PINK1 (fragment 52kD)@mitochondrion
- PINK1@mitochondrion
→
PINK1@mitochondrion
- PARK2:PINK1@mitochondrion
→
mitophagy@neuron
- NEDD8@neuron
→
PINK1@neuron
- MARK2@neuron
→
PINK1@mitochondrion
- PINK1@neuron
→
TRAF2:TRAF6@neuron
- PINK1@neuron
→
MAP3K7@neuron
- PARK2@neuron
+ PINK1@mitochondrion
→
PARK2:PINK1@mitochondrion
- PINK1@neuron
→
ubiquitin|S65_pho@neuron
- ROS@mitochondrion
→
PINK1@mitochondrion
- PINK1@mitochondrial matrix
→
degraded
- BECN1@neuron
+ PINK1@neuron
→
BECN1:PINK1@neuron
- BECN1:PINK1@neuron
→
BECN1:PIK3C3:PIK3R4@neuron
- PINK1@dendritic shaft
→
dendrite extension@dendritic shaft
- PINK1@dendritic shaft
→
mitochondrial motility@dendritic shaft
- PINK1@dendritic shaft
→
s8071
- PINK1@dendritic shaft
→
MAP2@dendritic shaft
- PINK1@mitochondrion
+ PARK2|ubi|active@neuron
→
PARK2:PINK1@mitochondrion
- PINK1@neuron
→
PINK1@neuron
- PINK1@neuron
→
degraded
- BCL2L1@neuron
+ PINK1@mitochondrion
→
BCL2L1:PINK1@mitochondrion
- BCL2L1:PINK1@mitochondrion
→
BCL2L1|S62_pho@neuron
- SREBF1@neuron
→
PINK1@mitochondrion
- TOMM20:TOMM22:TOMM40:TOMM5:TOMM6:TOMM7:TOMM70@mitochondrion
→
PINK1@mitochondrion
- PINK1@mitochondrion
+ PARK2|ubi|active@neuron
→
PARK2:PINK1@mitochondrion
- PINK1:nuclear RCC RNA@mitochondrion
→
s8616
- PUM1:nuclear RCC RNA@mitochondrion
+ PINK1@neuron
→
PINK1:nuclear RCC RNA@mitochondrion
+ PUM1@neuron
- PINK1@neuron
→
SIRT1@neuron
- PINK1@mitochondrion
→
s10479
- VPS13C@mitochondrion
→
PARK2:PINK1@mitochondrion
- PINK1@mitochondrion
+ PARK2|ubi|active@neuron
→
PARK2:PINK1@mitochondrion
- PINK1@mitochondrion
→
PARK2|ubi|active@neuron
- chaperone-mediated protein folding@mitochondrion
→
PINK1@mitochondrion
As Catalyser:- TOMM20:TOMM22:TOMM40:TOMM5:TOMM6:TOMM7:TOMM70@mitochondrion
→
TOMM40|ubi@neuron
+ TOMM20|ubi@neuron
+ TOMM70@neuron
- PARK2@neuron
→
PARK2|ubi|active@neuron
- VDAC1@mitochondrion
→
VDAC1|ubi@mitochondrion
- MFN1@mitochondrion
→
MFN1|ubi@neuron
- MFN2@mitochondrion
→
MFN2|ubi@neuron
- HDAC6@neuron
→
HDAC6@mitochondrion
- FIS1@mitochondrion
→
FIS1|ubi@mitochondrion
- TRAP1@mitochondrion
→
TRAP1|pho@mitochondrion
- HTRA2@mitochondrion
→
HTRA2|S400_pho|hm3|active@mitochondrion
- DNM1L@neuron
→
DNM1L|S637_pho@neuron
- RHOT1@mitochondrion
→
RHOT1|pho|ubi@neuron
- RHOT2@mitochondrion
→
RHOT2|pho|ubi@neuron
- PRKAR2B@Striatal Projection Neuron
→
PRKAR2B|pho@dendritic shaft
- HNRNPF:PUM1:nuclear RCC RNA@neuron
→
PUM1:nuclear RCC RNA@neuron
+ HNRNPF@neuron
- PUM1:nuclear RCC RNA@neuron
→
PUM1:nuclear RCC RNA@mitochondrion
- s8645 →
s11040
- NDUFA10@mitochondrion
→
(Fe-S protein:MT-ND1:MT-ND2:MT-ND3:MT-ND4:MT-ND4L:MT-ND5:MT-ND6:NDUFAB1:NDUFAF1:NDUFC1:NDUFC2:NDUFV1:NDUFV2:NDUFV3:alpha subcomplex:beta subcomplex)|active@mitochondrial matrix
- generic protein|oxidized@mitochondrial matrix
→
generic protein|oxidized@oxidized lipid membrane