Phenotype PI3K cascade map
PI3K cascade@microglia
Symbol:
Name: phosphatidylinositol 3-kinase signaling
Description:
Previous Symbols:
Synonyms:
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
Modifications:
In compartment: Striatal Projection Neuron
  1. PI3K cascade@Striatal Projection Neuron map
In compartment: microglia
  1. PI3K cascade@microglia map
  2. PI3K cascade@microglia map
In compartment: neuron
  1. PI3K cascade@neuron map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ADORA2A@Striatal Projection Neuron map → map PI3K cascade@Striatal Projection Neuron map
    2. PI3K cascade@neuron map → map PDPK1@neuron map
    3. WISP1@neuron map → map PI3K cascade@neuron map
    4. (IGF1R:​IRS1)|​active@neuron map → map PI3K cascade@neuron map
    5. PTEN@neuron map → map PI3K cascade@neuron map
    6. RTK activity@default map → map PI3K cascade@neuron map
    7. GPCR activity@default map → map PI3K cascade@neuron map
    8. cytosolic calcium ion homeostasis@neuron map → map PI3K cascade@neuron map
    9. (NGF:​NTRK1)|​active@neuron map → map PI3K cascade@neuron map
    10. GDNF:​GFRA1:​RET|​pho@neuron map → map PI3K cascade@neuron map
    11. ADORA2A@microglia map → map PI3K cascade@microglia map
    12. (ITGAM:​ITGB2)|​active@microglia map → map PI3K cascade@microglia map
    13. PI3K cascade@microglia map → map s7053
    As Catalyser:
    1. CYBA:​CYBB@microglia map + NCF1:​NCF2:​NCF4@microglia map + RAC1|​GTP@microglia map + RAC2|​GTP@microglia map → map (CYBA:​CYBB:​NCF1|​pho:​NCF2|​pho:​NCF4:​RAC1|​GTP:​RAC2|​GTP)|​active@microglia map