Protein RAB7A  
 
Modifications:
In compartment: Lewy body
- RAB7A@Lewy body 
 
 
In compartment: late endosome
- RAB7A@late endosome 
 
 - RAB7A|GDP@late endosome 
 
 - RAB7A|GTP@late endosome 
 
 
In compartment: neuron
- RAB7A@neuron 
 
 
Participates in complexes:
In compartment: late endosome
- RAB7A|GTP:retromer VPS sub-complex@late endosome 
 
 
In compartment: neuron
- LRRK2|mutated G2019S:RAB7A@neuron 
 
 
Participates in reactions:
As Reactant or Product:- RAB7A|GTP@late endosome 
  → 
  RAB7A|GDP@late endosome 
 
 - RAB7A|GDP@late endosome 
  → 
  RAB7A|GTP@late endosome 
 
 - VPS26A:VPS26B:VPS29:VPS35@late endosome 
  + RAB7A|GTP@late endosome 
  → 
  RAB7A|GTP:retromer VPS sub-complex@late endosome 
 
 - RAB7A|GTP:retromer VPS sub-complex@late endosome 
  + SNX1:SNX2:SNX32:SNX5:SNX6@late endosome 
  → 
  RAB7-bound VPS sub-complex:SNX-BAR sub-complex@late endosome 
 
 - RAB7A@neuron 
  → 
  RAB7A@late endosome 
 
 - RAB7A@neuron 
  + LRRK2|active|mutated G2019S@neuron 
  → 
  LRRK2|mutated G2019S:RAB7A@neuron 
 
 - RAB7A@neuron 
  + LRRK2|active|mutated G2019S@neuron 
  → 
  LRRK2|mutated G2019S:RAB7A@neuron 
 
 
As Catalyser:- s1338 → 
  s1332
 - s1339 → 
  s1338