Protein RAB7A
Modifications:
In compartment: Lewy body
- RAB7A@Lewy body
In compartment: late endosome
- RAB7A@late endosome
- RAB7A|GDP@late endosome
- RAB7A|GTP@late endosome
In compartment: neuron
- RAB7A@neuron
Participates in complexes:
In compartment: late endosome
- RAB7A|GTP:retromer VPS sub-complex@late endosome
In compartment: neuron
- LRRK2|mutated G2019S:RAB7A@neuron
Participates in reactions:
As Reactant or Product:- RAB7A|GTP@late endosome
→
RAB7A|GDP@late endosome
- RAB7A|GDP@late endosome
→
RAB7A|GTP@late endosome
- VPS26A:VPS26B:VPS29:VPS35@late endosome
+ RAB7A|GTP@late endosome
→
RAB7A|GTP:retromer VPS sub-complex@late endosome
- RAB7A|GTP:retromer VPS sub-complex@late endosome
+ SNX1:SNX2:SNX32:SNX5:SNX6@late endosome
→
RAB7-bound VPS sub-complex:SNX-BAR sub-complex@late endosome
- RAB7A@neuron
→
RAB7A@late endosome
- RAB7A@neuron
+ LRRK2|active|mutated G2019S@neuron
→
LRRK2|mutated G2019S:RAB7A@neuron
- RAB7A@neuron
+ LRRK2|active|mutated G2019S@neuron
→
LRRK2|mutated G2019S:RAB7A@neuron
As Catalyser:- s1338 →
s1332
- s1339 →
s1338