Protein XPA map

Identifiers
xeroderma pigmentosum, complementation group A
HUGO:XPA HGNC:12814 ENTREZ:7507 UNIPROT:P23025 GENECARDS:XPA REACTOME:67438 KEGG:7507 ATLASONC:XPAID104 WIKI:XPA

Maps_Modules
 dnarepair  map

References
PMID:22373527, PMID:23085398, PMID:22824526, PMID:22373527, PMID:22257761
PMID:19809470 PMID:15703371, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153, PMID:11900249

XPA|​S196_pho@Nucleus

References
d_re235( dnarepair  map ):
ATR phosphorylates XPA and activates NER during S-phase in response to damaged DNA, but not during other cc phases:
PMID:16540648, PMID:19004803

XPA@Nucleus

References
d_re235( dnarepair  map ):
ATR phosphorylates XPA and activates NER during S-phase in response to damaged DNA, but not during other cc phases:
PMID:16540648, PMID:19004803

Modifications:
In compartment: Nucleus
  1. XPA@Nucleus map
  2. XPA|​S196_pho@Nucleus map
Participates in complexes:
In compartment: default
  1. XAB2:​XPA|​S196_pho@default map
  2. CDK7:​CyclinH*:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@default map
  3. CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@default map
Participates in reactions:
As Reactant or Product:
  1. CDK7:​CyclinH*:​MNAT1:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XPB*:​XPD*@default map + RPA1:​RPA2|​pho:​RPA3@default map + XAB2:​XPA|​S196_pho@default map → map CDK7:​CyclinH*:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@default map
  2. CDK7:​CyclinH*:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@default map + ERCC1@default map + XPF*@default map + XPG*@default map → map CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@default map
  3. XPA|​S196_pho@Nucleus map + XAB2@Nucleus map → map XAB2:​XPA|​S196_pho@default map
  4. XPA@Nucleus map → map XPA|​S196_pho@Nucleus map
As Catalyser:
  1. gGG-NER_DNA_st2*@Nucleus map → map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  2. gTC-NER_DNA_st2*@Nucleus map → map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  3. gFanconi_DNA_st5*@Nucleus map → map gTC-NER_GG-NER_DNA_st4*@Nucleus map
  4. gTC-NER_GG-NER_DNA_st3*@Nucleus map → map gTC-NER_GG-NER_DNA_st4*@Nucleus map + Modified 24-32 nucleotides fragment@default map