Protein TDG map

Identifiers
thymine-DNA glycosylase
HUGO:TDG HGNC:11700 ENTREZ:6996 UNIPROT:Q13569 GENECARDS:TDG REACTOME:65813 ATLASONC:GC_TDG WIKI:TDG

Maps_Modules
 dnarepair  map

References
PMID:17129768, PMID:15703371, PMID:19847258, PMID:16697054, PMID:14726013

TDG|​don@default

References
d_re196( dnarepair  map ):
TDG SUMOlation causes dissociation of TDG from DNA to allow the next step of BER pathway by APE proteins.
PMID:16626738

TDG@default

References
d_re77:( dnarepair  map ) PMID:17129768
d_re196( dnarepair  map ):
TDG SUMOlation causes dissociation of TDG from DNA to allow the next step of BER pathway by APE proteins.
PMID:16626738
d_re480( dnarepair  map ):
9-1-1 complex activates TDG glycosylase and activates BER:
PMID:17855402

Modifications:
In compartment: default
  1. TDG@default map
  2. TDG|​don@default map
Participates in complexes:
In compartment: default
  1. RAD23*:​TDG:​XPC@default map
  2. HUS1:​RAD1:​RAD9*|​pho:​TDG@default map
Participates in reactions:
As Reactant or Product:
  1. TDG@default map → map TDG|​don@default map
  2. TDG|​don@default map → map degraded
  3. TDG@default map + HUS1:​RAD1:​RAD9*|​pho@default map → map HUS1:​RAD1:​RAD9*|​pho:​TDG@default map
  4. TDG@default map + XPC@default map + RAD23*@default map → map RAD23*:​TDG:​XPC@default map
As Catalyser:
  1. gDeaminated_alkylated_mismatched_base*@Nucleus map → map gBER_M-glyc_DNA_st2*@Nucleus map + Base@default map