Identifiers
cyclin-dependent kinase 4
HUGO:CDK4 HGNC:1773 ENTREZ:1019 UNIPROT:P11802 GENECARDS:CDK4 REACTOME:68329 KEGG:1019 ATLASONC:CDK4ID238ch12q14 WIKI:CDK4
Cyclin-dependent kinase 6
HUGO:CDK6 HGNC:1777 ENTREZ:1021 UNIPROT:Q00534 GENECARDS:CDK6 REACTOME:68335 KEGG:1021 ATLASONC:GC_CDK6 WIKI:CDK6

Maps_Modules
 emtcellmotility 
 dnarepair 
 survival 

References
PMID:20068082, PMID:16236519, PMID:18590585, PMID:19075565, PMID:18786381, PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786

1. CDK4_6*@default

1. CDK4_6*:​INK4*@default
2. CDK4_6*:​CyclinD*@default
3. CDK4_6*:​CyclinD*|​pho@default
4. CDK4_6*|​Y14_pho:​CyclinD*@default
5. CDK4_6*|​T172_pho|​Y14_pho:​CyclinD*@default
6. (CDK4_6*|​T172_pho:​CyclinD*)|​active@default
7. (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@default

1. CyclinD*@default + CDK4_6*@default → CDK4_6*:​CyclinD*@default
2. CDK4_6*@default + INK4*@default → CDK4_6*:​INK4*@default
3. (CDK4_6*|​T172_pho:​CyclinD*)|​active@default + CIP1_KIP1*@default → (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@default
4. (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@default → CIP1_KIP1*@default + (CDK4_6*|​T172_pho:​CyclinD*)|​active@default
5. CDK4_6*:​INK4*@default → INK4*@default + CDK4_6*@default
6. CDK4_6*:​CyclinD*@default → CDK4_6*|​Y14_pho:​CyclinD*@default
7. CDK4_6*|​Y14_pho:​CyclinD*@default → CDK4_6*|​T172_pho|​Y14_pho:​CyclinD*@default
8. CDK4_6*|​T172_pho|​Y14_pho:​CyclinD*@default → (CDK4_6*|​T172_pho:​CyclinD*)|​active@default
9. CDK4_6*:​CyclinD*@default → CDK4_6*:​CyclinD*|​pho@default
10. CDK4_6*:​CyclinD*|​pho@default → CyclinD*|​pho@default + CDK4_6*@default

1. G1 phase@default → S phase@default
2. E2F1:​RB1@default → E2F1:​RB1|​pho@default
3. E2F4_5*:​p107*@default → E2F4_5*:​p107*|​pho@default