Reaction state_transition d_re195 map

FANCM|​pho@default map → degraded

Reaction regulators:
Catalysis
  1. CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map
Trigger
  1. M phase@default map


References
FANCM is phosphorylated by PLK1 and beta-TRCP in response to G2/M checkpoint. Phosphorylated FANCM is degraded and FANCONI pathway is inhibited during mitosis.
PMID:19270156

Confidence
REF=1 FUNC=4