Complex CUL1:RBX1:SKP1:SKP2:_beta_TRCP* map
Complex composition:

  1. _beta_TRCP* map
  2. SKP1 map
  3. CUL1 map
  4. RBX1 map
  5. SKP2 map

CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default

Identifiers
NAME:CUL1:RBX1:SKP1:SKP2:_beta_TRCP*

Maps_Modules
 dnarepair  map
 dnarepair  map
 dnarepair  map

References
FANCM is phosphorylated by PLK1 and ubiquitinated by beta-TRCP (in the SCF complex) in response to G2/M checkpoint. Phosphorylated FANCM is degraded and FANCONI pathway is inhibited during mitosis.
PMID:19270156, PMID:19686080, PMID:15459660
d_re195( dnarepair  map ):
FANCM is phosphorylated by PLK1 and beta-TRCP in response to G2/M checkpoint. Phosphorylated FANCM is degraded and FANCONI pathway is inhibited during mitosis.
PMID:19270156

Confidence
REF=1 FUNC=5

Modifications:
Participates in complexes:
In compartment: default
  1. CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map
Participates in reactions:
As Reactant or Product:
  1. _beta_TRCP*@default map + SKP1@default map + CUL1@default map + RBX1@default map + SKP2@default map → map CUL1:​RBX1:​SKP1:​SKP2:​_beta_TRCP*@default map
As Catalyser:
  1. FANCM|​pho@default map → map degraded
  2. CyclinD*@default map → map degraded
  3. CyclinE*@default map → map degraded
  4. CDC25A@default map → map degraded
  5. CDC25B@default map → map degraded
  6. WEE1|​pho@default map → map degraded
  7. EMI1*|​pho@default map → map degraded