Protein TLR5
TLR5 is the receptor for flagellin, the protein that forms bacterial flagella. TLR5 is expressed on epithelial cells as well as on macrophages and dendritic cells. Expression of TLR5 on intestinal epithelium is polarized such that TLR5 is expressed only on the basolateral side of the cell.
TLR5@Cytoplasm
GeneID:7100
Modifications:
In compartment: Cytoplasm
- TLR5@Cytoplasm
Participates in complexes:
In compartment: Cytoplasm
- MYD88:TIRAP:TLR5@Cytoplasm
- IRAK1:IRAK4:TIRAP:TLR5@Cytoplasm
Participates in reactions:
As Reactant or Product:- flagellin@default
→
TLR5@Cytoplasm
- TLR5@Cytoplasm
+ MYD88@Cytoplasm
+ TIRAP@Cytoplasm
→
MYD88:TIRAP:TLR5@Cytoplasm
- MYD88:TIRAP:TLR5@Cytoplasm
+ IRAK4@Cytoplasm
+ IRAK1@Cytoplasm
→
IRAK1:IRAK4:TIRAP:TLR5@Cytoplasm
- IRAK1:IRAK4:TIRAP:TLR5@Cytoplasm
→
IRAK1|pho|pho|pho@Cytoplasm
As Catalyser: