Complex IL-1RAcP:IL-1RI:IL-1RI_br_ligand
Complex composition:
- IL-1RI_br_ligand
- IL-1RI
- IL-1RAcP
Modifications:
Participates in complexes:
In compartment: cytosol
- (IL-1RAcP:IL-1RI:IL-1RI_br_ligand)|active@cytosol
- (IL-1RAcP:IL-1RI_br_ligand:IL-1RI|Y479_pho)|active@cytosol
Participates in reactions:
As Reactant or Product:- (IL-1RAcP:IL-1RI:IL-1RI_br_ligand)|active@cytosol
→
(IL-1RAcP:IL-1RI_br_ligand:IL-1RI|Y479_pho)|active@cytosol
- IL-1RAcP@cytosol
+ IL-1RI:IL-1RI_br_ligand@cytosol
→
(IL-1RAcP:IL-1RI:IL-1RI_br_ligand)|active@cytosol
As Catalyser:- TIR domain@cytosol
+ MyD88|hm2@cytosol
→
MyD88|hm2:TIR domain@cytosol
- PI3K (p110):PI3K (p85)@cytosol
→
PI3K (p110):PI3K(p85)*@cytosol
- (GTP:Rac1)|active@cytosol
→
(GTP:Rac1*)|active@cytosol
- (GTP:RhoA)|active@cytosol
→
(GTP:RhoA*)|active@cytosol
- IRAK4:MyD88|hm2:TIR domain@cytosol
+ IRAK1:TOLLIP@cytosol
→
IRAK1:IRAK4:MyD88|hm2:TIR domain:TOLLIP@cytosol
- PKC_zeta:p62@cytosol
+ IRAK1|T209_pho|T387_pho|ubi:TIFA:TRAF6|ubi|hm2:Ubc13:Uev1A@cytosol
+ Ajuba@cytosol
→
Ajuba:IRAK1|T209_pho|T387_pho|ubi:PKC_zeta:TIFA:TRAF6|ubi|hm2:Ubc13:Uev1A:p62@cytosol