Protein TOLLIP

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Modifications:
In compartment: cytosol

1. TOLLIP@cytosol
2. TOLLIP|​pho@cytosol
3. TOLLIP|​pho|​ubi@cytosol

Participates in complexes:
In compartment: cytosol

1. IRAK1:​TOLLIP@cytosol
2. IRAK1c:​TOLLIP@cytosol
3. IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
4. IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
5. IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
6. IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
7. IRAK1c:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
8. IRAK1c:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP:​TRAF6|​hm2@cytosol
9. IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
10. IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol

Participates in reactions:
As Reactant or Product:

1. IRAK1@cytosol + TOLLIP@cytosol → IRAK1:​TOLLIP@cytosol
2. TOLLIP|​pho@cytosol → TOLLIP|​pho|​ubi@cytosol
3. TOLLIP|​pho|​ubi@cytosol → degraded
4. IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP@cytosol + IRAK1:​TOLLIP@cytosol → IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
5. IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol → IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
6. IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol → IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
7. IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol → IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP@cytosol + TOLLIP|​pho@cytosol
8. IRAK1c@cytosol + TOLLIP@cytosol → IRAK1c:​TOLLIP@cytosol
9. TOLLIP@cytosol → TOLLIP*@cytosol
10. IRAK1c:​TOLLIP@cytosol + TRAF6|​hm2@cytosol + IRAK4:​MyD88|​hm2:​TIR domain@cytosol → IRAK1c:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP:​TRAF6|​hm2@cytosol
11. IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP@cytosol + IRAK1c:​TOLLIP@cytosol → IRAK1c:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
12. IRAK4:​MyD88|​hm2:​TIR domain@cytosol + IRAK1:​TOLLIP@cytosol → IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
13. IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol → IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
14. IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol → IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
15. IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol → TOLLIP|​pho@cytosol + IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain@cytosol
16. TOLLIP|​pho@cytosol → degraded

As Catalyser:

1. IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol → IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
2. IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol → IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol
3. IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP:​TOLLIP@cytosol → IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TIRAP@cytosol + TOLLIP|​pho@cytosol
4. IRAK1:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol → IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
5. IRAK1|​T209_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol → IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol
6. IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain:​TOLLIP@cytosol → TOLLIP|​pho@cytosol + IRAK1|​T209_pho|​T387_pho:​IRAK4:​MyD88|​hm2:​TIR domain@cytosol