Reaction heterodimer_association re539
MyD88|hm2@cytosol
+ TRAF6|hm2@cytosol
+ IRF7@cytosol
→ IRF7:MyD88|hm2:TRAF6|hm2@cytosol
Reaction regulators:
- Catalysis
- (TLR7 ligand:TLR7|hm2)|active@endosome
- TLR9 ligand:TLR9|hm2@late endosome
- (TLR8 ligand:TLR8|hm2)|active@endosome
PMID:15361868