Complex NFKB1_p50*:cREL*:p100 map
Complex composition:

  1. cREL* map
  2. NFKB1_p50* map
  3. p100 map

CD247:​NFKB1_p50*:​p100@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:CD247:NFKB1_p50*:p100

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
 DENDRITIC_CELL  map
PMID:25305492
p19 and p40 subunits of IL-23, a c-Rel-dependent cytokine, was enhanced in p100-deficient cells, although expression of a RelA-dependent cytokine, TNF-α, was reduced. Nuclear translocation of c-Rel was enhanced in p100-deficient cells. p100, and not the processed p52 form, associated with c-Rel in the steady state and dissociated immediately after lipopolysaccharide stimulation in wild-type dendritic cells. Four hours after the stimulation, p100 was newly synthesized and associated with c-Rel again. In cells expressing both c-Rel and RelA, c-Rel is preferentially suppressed by p100.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CD247:​NFKB1_p50*:​p100@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. CD247:​NFKB1_p50*:​p100@INNATE_IMMUNE_CELL_Cytosol map → map NFKB1_p50*:​cREL*@INNATE_IMMUNE_CELL_Cytosol map + p100@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: