Antisense RNA MIR20A map

Identifiers
HUGO:MIR20A

Maps_Modules
MODULE:INPUT_INHIBITORS MODULE:IMMUNE_SUPPRESSION MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS MODULE:CORE_SIGNALING_PATHWAYS MODULE:MIRNA_TF_IMMUNOSUPPRESSIVE

References
 NATURAL_KILLER  map
PMID:25277195, PMID:24813230
Inhibition of MIR20A or MIR93 upregulates translation of their predicted targets (MICA, MICB, ULBP2 or ULBP3) in tumor cells and upregulates NK cytotoxicity against these cells.
PMID:21383238
Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells and macrophages by modulating STAT3 expression.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR20A@INNATE_IMMUNE_CELL_Cytosol map
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. arMIR20A@TUMOR_CELL_AS_INDUCTOR map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map + arMIR20A@INNATE_IMMUNE_CELL_Cytosol map → map MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
  2. MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map → map degraded
As Catalyser:
  1. rULBP2@TUMOR_CELL_AS_INDUCTOR map → map ULBP2@TUMOR_CELL_AS_INDUCTOR map
  2. rMICA@TUMOR_CELL_AS_INDUCTOR map → map MICA@TUMOR_CELL_AS_INDUCTOR map
  3. rMICB@TUMOR_CELL_AS_INDUCTOR map → map MICB@TUMOR_CELL_AS_INDUCTOR map
  4. rUDLP3@TUMOR_CELL_AS_INDUCTOR map → map ULBP3@TUMOR_CELL_AS_INDUCTOR map