RNA STAT3 map

Identifiers
HUGO:STAT3

Maps_Modules
MODULE:INPUT_INHIBITORS MODULE:IMMUNE_SUPPRESSION MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS MODULE:INPUT_ACTIVATORS MODULE:IMMUNE_STIMULATION MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
 MACROPHAGE  map
 NEUTROPHIL  map
 MDSC  map
 DENDRITIC_CELL  map
CASCADE:IL10
CASCADE:FLT3LG
CASCADE:IFNAB
PMID:21383238
Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells by modulating STAT3 expression.
miR-17-5p and miR-20a also reduced the transcriptional and protein levels of p47phox and gp91phox, two subunits of NADPH oxidase.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MIR17:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
  2. MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. gSTAT3@INNATE_IMMUNE_CELL_Cytosol map → map rSTAT3@INNATE_IMMUNE_CELL_Cytosol map
  2. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map → map STAT3@INNATE_IMMUNE_CELL_Cytosol map
  3. gSTAT3@INNATE_IMMUNE_CELL_Cytosol map → map rSTAT3@INNATE_IMMUNE_CELL_Cytosol map
  4. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map → map STAT3@INNATE_IMMUNE_CELL_Cytosol map
  5. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map + arMIR20A@INNATE_IMMUNE_CELL_Cytosol map → map MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
  6. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map + arMIR17@INNATE_IMMUNE_CELL_Cytosol map → map MIR17:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
  7. MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  8. MIR17:​STAT3@INNATE_IMMUNE_CELL_Cytosol map → map degraded
As Catalyser: