RNA TGFB1 map

Identifiers
HUGO:TGFB1

Maps_Modules
MODULE:INPUT_INHIBITORS
MODULE:IMMUNE_SUPPRESSION
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS
MODULE:EFFECTOR_INHIBITION
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_EXPRESSION
 MACROPHAGE  map
 MDSC  map
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
CASCADE:TGFB
CASCADE:STING

References
PMID:16327802
IL13 and TNF inducese TGFB1 expression via AP-1 transcription factors.IL13 induces binding of c-jun and fra2 ti TGFB1 promotor, and TNF binding of c-jun, JunD and c-fos
PMID:20644162
Cytokine-induced CD33+ human MDSCs have upregulated iNOS, TGFβ, VEGF.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rTGFB1@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gTGFB1@INNATE_IMMUNE_CELL_Cytosol map → map rTGFB1@INNATE_IMMUNE_CELL_Cytosol map
    2. rTGFB1@INNATE_IMMUNE_CELL_Cytosol map → map TGFB1@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: