Protein ITGB1 map

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:INTEGRINS

References
 NATURAL_KILLER  map
CASCADE:INTEGRIN_A4B1
CASCADE:INTEGRIN_A5B1
PMID:19454690
NKG2D ligation leads to increased adhesion and recruitment of beta1 and beta2 integrins to the cytotoxic synapse.
PMID:9973479
Beta 1 integrin cross-linking inhibits CD16-induced phospholipase D and secretory phospholipase A2 activity and granule exocytosis in human NK cells.
PMID:9763606
Cross-linking of β1 Integrins on Human NK Cells Induces Shc Tyrosine Phosphorylation and Grb2 Association via Pyk-2end
resulted in RAS/ERK activation.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. ITGB1@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. ITGA5:​ITGB1@INNATE_IMMUNE_CELL_Membrane map
  2. (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map
  3. FN1:​ITGA5:​ITGB1@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map → map (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map
  2. ITGB1@INNATE_IMMUNE_CELL_Membrane map + ITGA4@INNATE_IMMUNE_CELL_Membrane map → map (ITGA4:​ITGB1)|​active@INNATE_IMMUNE_CELL_Membrane map
  3. FN1@default map + ITGA5:​ITGB1@INNATE_IMMUNE_CELL_Membrane map → map FN1:​ITGA5:​ITGB1@INNATE_IMMUNE_CELL_Membrane map
  4. ITGB1@INNATE_IMMUNE_CELL_Membrane map + ITGA5@INNATE_IMMUNE_CELL_Membrane map → map ITGA5:​ITGB1@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. ZAP70@INNATE_IMMUNE_CELL_Cytosol map → map ZAP70|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  2. FYN@INNATE_IMMUNE_CELL_Cytosol map → map FYN|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  3. PTK2B@INNATE_IMMUNE_CELL_Cytosol map → map PTK2B|​pho@INNATE_IMMUNE_CELL_Cytosol map
  4. PLD*@INNATE_IMMUNE_CELL_Cytosol map → map PLD*@INNATE_IMMUNE_CELL_Cytosol map
  5. PLA2G2A@INNATE_IMMUNE_CELL_Cytosol map → map PLA2G2A|​pho@INNATE_IMMUNE_CELL_Cytosol map
  6. PTK2@INNATE_IMMUNE_CELL_Cytosol map → map PTK2@INNATE_IMMUNE_CELL_Cytosol map
  7. LYN@INNATE_IMMUNE_CELL_Cytosol map → map LYN|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map