Protein DEPTOR
Identifiers
HUGO:DEPTOR
Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS
References
NATURAL_KILLER
DENDRITIC_CELL
PMID:16469695, PMID:26159692
mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8) and the recently identified PRAS40 and DEPTOR
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- DEPTOR:MLST8:ORP1L*:PRAS40*:RILP@INNATE_IMMUNE_CELL_Cytosol
- (DEPTOR:MLST8:MTOR|pho:PRAS40*:RPTOR)|active@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- DEPTOR:MLST8:ORP1L*:PRAS40*:RILP@INNATE_IMMUNE_CELL_Cytosol
→
(DEPTOR:MLST8:MTOR|pho:PRAS40*:RPTOR)|active@INNATE_IMMUNE_CELL_Cytosol
As Catalyser:- IFNG@INNATE_IMMUNE_CELL_Cytosol
→
IFNG@default
- GZMB@SECRETORY_GRANULE
→
GZMB@default
- GZMA@SECRETORY_GRANULE
→
GZMA@default
- gIL10@INNATE_IMMUNE_CELL_Cytosol
→
rIL10@INNATE_IMMUNE_CELL_Cytosol