Protein GSK3*
Identifiers
HUGO:GSK3A
HUGO:GSK3B
Maps_Modules
MACROPHAGE
MODULE:CORE_SIGNALING_PATHWAYS
MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS
CASCADE:IFNG
References
PMID:16713974
AKT kinases phosphorylate GSK3 proteins and inhibit its activity downstream of TLR signaling.
IFNG prevents this inactivation.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- GSK3*@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- GSK3_alpha_*@INNATE_IMMUNE_CELL_Cytosol
→
GSK3*@INNATE_IMMUNE_CELL_Cytosol
- GSK3_beta_*@INNATE_IMMUNE_CELL_Cytosol
→
GSK3*@INNATE_IMMUNE_CELL_Cytosol
As Catalyser:- AP1*@INNATE_IMMUNE_CELL_Cytosol
→
AP1*|pho|active@INNATE_IMMUNE_CELL_Cytosol
- _beta_-Catenin*@INNATE_IMMUNE_CELL_Cytosol
→
_beta_-Catenin*|pho|active@INNATE_IMMUNE_CELL_Cytosol