Complex ITGAV:ITGB3 map
Complex composition:

  1. ITGAV map
  2. ITGB3 map

ITGAV:​ITGB3@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:ITGAV:ITGB3

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:DANGER_SIGNAL_PATHWAYS MODULE:INTEGRINS

References
CASCADE:INTEGRIN_AVB3
 DENDRITIC_CELL  map
PMID:9295024, PMID:9763615
Dendritic cells phagocytose apoptotic cells via alphavbeta5, alphavbeta3, and CD36.
and cross-present Antigens to Cytotoxic T Lymphocytes
The interaction between apoptotic bodies and dendritic cells elicits a rise in intracellular free calcium concentration ([Ca2+]i) which is essential for the process of engulfment.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. ITGAV:​ITGB3@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. PtdSer@TUMOR_CELL_AS_INDUCTOR_Membrane map + MFGE8@TUMOR_CELL_AS_INDUCTOR_Membrane map + ITGAV:​ITGB3@INNATE_IMMUNE_CELL_Membrane map → map ITGAV:​ITGB3:​MFGE8:​PtdSer@INNATE_IMMUNE_CELL_Membrane map
As Catalyser: