Complex CLEC2B:NKp80* map
Complex composition:

  1. CLEC2B map
  2. NKp80* map

CLEC2B:​NKp80*|​hm2@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:CLEC2B:NKp80*

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:NK_ACTIVATING_RECEPTORS

References
CASCADE:NKP80
 NATURAL_KILLER  map
20663776, 17057721
C-type lectin (AICL) is a unique KLRF1 ligand expressed on tumor cell lines of hematopoietic and non-hematopoietic origins.
20663776
Blocking of CLEC2B (AICL) partially inhibits NK cell degranulation (LAMP1/CD107a presentation).
11265639
Nkp80 signaling pathway induces Ca2+ mobilization and NK cell-mediated cytolytic activity.

(CLEC2B:​NKp80*|​pho|​hm2)|​active@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:CLEC2B:NKp80*

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:NK_ACTIVATING_RECEPTORS

References
CASCADE:NKP80
 NATURAL_KILLER  map
20663776, 17057721
C-type lectin (AICL) is a unique KLRF1 ligand expressed on tumor cell lines of hematopoietic and non-hematopoietic origins.
20663776
Blocking of CLEC2B (AICL) partially inhibits NK cell degranulation (LAMP1/CD107a presentation).
11265639
Nkp80 signaling pathway induces Ca2+ mobilization and NK cell-mediated cytolytic activity.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CLEC2B:​NKp80*|​hm2@INNATE_IMMUNE_CELL_Membrane map
  2. (CLEC2B:​NKp80*|​pho|​hm2)|​active@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. NKp80*|​hm2@INNATE_IMMUNE_CELL_Membrane map + CLEC2B@TUMOR_CELL_AS_INDUCTOR_Membrane map → map CLEC2B:​NKp80*|​hm2@INNATE_IMMUNE_CELL_Membrane map
  2. CLEC2B:​NKp80*|​hm2@INNATE_IMMUNE_CELL_Membrane map → map (CLEC2B:​NKp80*|​pho|​hm2)|​active@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. IFNG@INNATE_IMMUNE_CELL_Cytosol map → map IFNG@default map
  2. SYK@INNATE_IMMUNE_CELL_Cytosol map → map SYK|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
  3. Ca2+@Endoplasmic Reticulum map → map Ca2+@INNATE_IMMUNE_CELL_Cytosol map