RNA MHC class II* map

Identifiers
HUGO:HLA-DMA HUGO:HLA-DMB HUGO:HLA-DOA HUGO:HLA-DOB HUGO:HLA-DPA1 HUGO:HLA-DPB1 HUGO:HLA-DQA1 HUGO:HLA-DQA2 HUGO:HLA-DQB1 HUGO:HLA-DQB2 HUGO:HLA-DRA HUGO:HLA-DRB1 HUGO:HLA-DRB3 HUGO:HLA-DRB4 HUGO:HLA-DRB5

Maps_Modules
MODULE:IMMUNE_STIMULATION MODULE:ANTIGEN_PRESENTATION MODULE:EFFECTOR_ACTIVATION

References
 DENDRITIC_CELL  map
 MACROPHAGE  map
CASCADE:MIF
CASCADE:IL10
CASCADE:CSF2
CASCADE:IFNG
PMID:23390297
MIF inhitits expression of M1 markers such as TNF, IL12p40, COX2, INOS, IRF-5, MHC-II, CD11c, CD80, CD86 and MIF induces expression of M2 markers as IL10, stabilin-1, MRC-1, CD206, CD23
PMID:22076556, PMID:22076556, PMID:25720354
Like MHC class I molecules, class II molecules are also heterodimers, but in this case consist of two homogenous peptides, an α and β chain, both of which are encoded in the MHC.
MHC class II molecules present antigen peptides to CD4+ T cells

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rMHC class II*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMHC class II*@INNATE_IMMUNE_CELL_Cytosol map → map rMHC class II*@INNATE_IMMUNE_CELL_Cytosol map
    2. rMHC class II*@INNATE_IMMUNE_CELL_Cytosol map → map MHC_class_II*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: