Ion Mn2+ map
Modifications:
In compartment: mitochondrial matrix
  1. Mn2+@mitochondrial matrix map
In compartment: neuron
  1. Mn2+@neuron map
Participates in complexes:
In compartment: mitochondrial matrix
  1. IDH2:​Mn2+@mitochondrial matrix map
  2. IDH2|​ace:​Mn2+@mitochondrial matrix map
  3. Ca2+:​IDH3A:​IDH3B:​IDH3G:​Mn2+@mitochondrial matrix map
Participates in reactions:
As Reactant or Product:
  1. cellular manganese ion homeostasis@neuron map → map Mn2+@neuron map
  2. Mn2+@neuron map → map neuron death@neuron map
  3. Mn2+@neuron map → map ATP13A2@neuron map
  4. IDH2|​ace:​Mn2+@mitochondrial matrix map → map IDH2:​Mn2+@mitochondrial matrix map
As Catalyser:
  1. (S)-2-hydroxyglutaric acid@mitochondrial matrix map + FAD@mitochondrial matrix map → map 2-oxoglutaric acid@mitochondrial matrix map + FADH2@mitochondrial matrix map
  2. isocitric acid@mitochondrial matrix map + NAD(+)@mitochondrial matrix map → map 2-oxoglutaric acid@mitochondrial matrix map + NADH@mitochondrial matrix map + CO2@mitochondrial matrix map + H+@mitochondrial matrix map
  3. isocitric acid@mitochondrial matrix map + NADP(+)@mitochondrial matrix map → map H+@mitochondrial matrix map + NADPH@mitochondrial matrix map + CO2@mitochondrial matrix map + 2-oxoglutaric acid@mitochondrial matrix map