Protein generic protein
Modifications:
In compartment: ER
- generic protein@ER
- generic protein|unfolded@ER
- generic protein|misfolded@ER
In compartment: default
- generic protein@default
In compartment: mitochondrial matrix
- generic protein@mitochondrial matrix
- generic protein|oxidized@mitochondrial matrix
- generic protein|misfolded@mitochondrial matrix
In compartment: neuron
- generic protein@neuron
- generic protein|ubi@neuron
- generic protein|ubi@neuron
- generic protein|oxidized@neuron
- generic protein|misfolded@neuron
- generic protein|S-glutathione@neuron
- generic protein|ubi|ubi|ubi@neuron
In compartment: oxidized lipid membrane
- generic protein|oxidized@oxidized lipid membrane
Participates in complexes:
In compartment: ER
- HSPA5:generic protein|misfolded@ER
- (ERN2|hm2:generic protein|misfolded)|active@ER
In compartment: neuron
- SQSTM1:generic protein|ubi|ubi|ubi@neuron
- HSPA4|ADP:generic protein|ubi|ubi|ubi@neuron
Participates in reactions:
As Reactant or Product:- generic protein|ubi|ubi|ubi@neuron
→
degraded + ubiquitin@neuron
- generic protein|ubi@neuron
+ ubiquitin@neuron
→
generic protein|ubi|ubi|ubi@neuron
- generic protein@neuron
+ ubiquitin@neuron
→
generic protein|ubi@neuron
- s4167 →
generic protein@neuron
- generic protein|ubi@neuron
→
generic protein@neuron
+ ubiquitin@neuron
- generic protein|ubi|ubi|ubi@neuron
→
generic protein|ubi@neuron
- glutathione@neuron
+ generic protein|oxidized@neuron
→
generic protein|S-glutathione@neuron
- generic protein|S-glutathione@neuron
→
generic protein@default
- generic protein@neuron
→
generic protein|oxidized@neuron
- generic protein|S-glutathione@neuron
→
generic protein@neuron
+ glutathione disulfide@neuron
- generic protein|oxidized@neuron
→
degraded
- generic protein|oxidized@neuron
+ TXN@neuron
→
generic protein@neuron
+ TXN|oxidized@neuron
- SQSTM1@neuron
+ generic protein|ubi|ubi|ubi@neuron
→
SQSTM1:generic protein|ubi|ubi|ubi@neuron
- generic protein|ubi|ubi|ubi@neuron
+ HSPA4|ATP@neuron
→
HSPA4|ADP:generic protein|ubi|ubi|ubi@neuron
- HSPA4|ADP:generic protein|ubi|ubi|ubi@neuron
+ HSPB8@neuron
+ BAG3@neuron
+ STUB1@neuron
→
BAG3:HSPA4:ADP:protein:HSPB8:STUB1@neuron
- MAP1LC3B@neuron
+ SQSTM1:generic protein|ubi|ubi|ubi@neuron
→
MAP1LC3B:SQSTM1:protein@neuron
- BAG3:HSPA4:ADP:protein:HSPB8:STUB1@neuron
→
generic protein|ubi|ubi|ubi@neuron
- HTRA2@mitochondrion
→
generic protein|misfolded@mitochondrial matrix
- generic protein|misfolded@neuron
→
degraded
- generic protein|misfolded@ER
+ HSPA5@ER
→
HSPA5:generic protein|misfolded@ER
- generic protein|misfolded@mitochondrial matrix
→
mt UPR@mitochondrial matrix
- generic protein|misfolded@mitochondrial matrix
→
generic protein@mitochondrial matrix
- generic protein|misfolded@ER
+ ERN2@ER
→
(ERN2|hm2:generic protein|misfolded)|active@ER
- (ERN2|hm2:generic protein|misfolded)|active@ER
→
apoptosis@neuron
- HSPA4|ADP:generic protein|ubi|ubi|ubi@neuron
→
generic protein|ubi|ubi|ubi@neuron
- generic protein|ubi@neuron
→
HDAC6:HSF1|K80_ace:HSP40:HSP70:HSP90:PTGES3@neuron
- generic protein|ubi@neuron
→
degraded
- generic protein|misfolded@ER
→
generic protein|misfolded@neuron
- generic protein|misfolded@ER
→
ER Stress@ER
- generic protein|unfolded@ER
+ PDIA2|active|oxidized@ER
→
generic protein@ER
+ PDIA2|reduced@ER
- generic protein|misfolded@ER
+ glutathione@ER
→
generic protein|unfolded@ER
+ glutathione disulfide@ER
- ROS@mitochondrial matrix
→
generic protein|oxidized@mitochondrial matrix
- generic protein|oxidized@mitochondrial matrix
→
generic protein|oxidized@oxidized lipid membrane
As Catalyser:- SIRT3@mitochondrial matrix
→
SIRT3@mitochondrial matrix