Phenotype MAPK cascade map
MAPK cascade@microglia
Symbol:
Name: MAPK cascade
Description:
Previous Symbols:
Synonyms:
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
Modifications:
In compartment: microglia
  1. MAPK cascade@microglia map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. TLR4@microglia map → map MAPK cascade@microglia map
    2. AGER@microglia map → map MAPK cascade@microglia map
    3. s12121 → map MAPK cascade@microglia map
    4. TLR3@microglia map → map MAPK cascade@microglia map
    5. TLR2@microglia map → map MAPK cascade@microglia map
    6. LRRK2@microglia map → map MAPK cascade@microglia map
    7. MAPK cascade@microglia map → map s11239
    8. ROS@microglia map → map MAPK cascade@microglia map
    As Catalyser: