+ Ku70*@default + WRN@Nucleus + DNA-PK*@default → DNA-PK*:Ku70*:Ku80*:WRN@Nucleus References
Binding between Ku70/80/DNA-PK and WRN inhibits Ku activity
PMID:17303082
PMID:12202749
WRN is a key activator of alt_NHEJ pathway
PMID:18524993
C_NHEJ and A_NHEJ are competing mechanisms
PMID:24050180
Confidence
REF=3 FUNC=5