Protein MDM2 map

Identifiers
Mdm2 p53 binding protein homolog (mouse)
HUGO:MDM2 HGNC:6973 ENTREZ:4193 UNIPROT:Q00987 GENECARDS:MDM2 REACTOME:95018 KEGG:4193 ATLASONC:MDM2ID115ch12q15 WIKI:MDM2

Maps_Modules
 emtcellmotility  map
 apoptosis  map
 dnarepair  map
 cellcycle  map
 cellcycle  map
 survival  map
 survival  map
 survival  map

References
PMID:14761977, PMID:11779693, PMID:17110379, PMID:9450543, PMID:15876864

MDM2|​pho@default

References
d_re49:( dnarepair  map ) PMID:19788416

MDM2@default

References
d_re48( dnarepair  map ):
BRCA1 stabilises p53 and causes activation of p53-dependent DNA-repair genes and activation of checkpoint, but no apoptoss:
PMID:12024039 , PMID:12496474
d_re49:( dnarepair  map ) PMID:19788416
d_re554:( dnarepair  map ) PMID:21727086, PMID:21922195, PMID:20724832

Modifications:
In compartment: default
  1. MDM2@default map
  2. MDM2|​pho@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. MDM2@default map → map MDM2|​pho@default map
    2. MDM2|​pho@default map → map degraded
    As Catalyser:
    1. p53*@default map → map degraded
    2. APE*@default map → map APE*|​Thr233_pho|​ubi@default map