Protein HCLK2* map

Identifiers
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
Protein clk-2 homolog , HCLK2
HUGO:TELO2 HGNC:29099 ENTREZ:9894 UNIPROT:Q9Y4R8 GENECARDS:TELO2 KEGG:9894 WIKI:TELO2

Maps_Modules
 dnarepair  map

References
PMID:19686080, PMID:19622404, PMID:18931676
For regulation of Fanconi pathway via cell cycle
PMID:18995830, PMID:17384638
For S-phase checkpoint
PMID:17384638, PMID:19793801
HCLK2*/FANCM/FAAP24/active ATR complex inhibits S-phase
PMID:19282663, PMID:19622404

HCLK2*@default

References
d_re199( dnarepair  map ):
HCLK2*/FANCM/FAAP24/active ATR complex inhibit S-phase:
PMID:19282663, PMID:19622404, PMID:18995830
d_re463( dnarepair  map ):
Arrests cell cycle in S-phase in response to stalled replication fork or ds breaks in DNA:
PMID:15459660, PMID:17384638, PMID:19793801

Modifications:
In compartment: default
  1. HCLK2*@default map
Participates in complexes:
In compartment: default
  1. ATR|​pho:​FAAP24*:​FANCM:​HCLK2*@default map
  2. ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​HCLK2*@default map
Participates in reactions:
As Reactant or Product:
  1. HCLK2*@default map + FAAP24*@default map + FANCM@default map + ATR|​pho|​active@Nucleus map → map ATR|​pho:​FAAP24*:​FANCM:​HCLK2*@default map
  2. HCLK2*@default map + CLSPN|​pho@default map + ATRIP:​ATR|​pho@default map + CHEK1|​pho|​active@default map → map ATRIP:​ATR|​pho:​CHEK1|​pho:​CLSPN|​pho:​HCLK2*@default map
As Catalyser:
  1. S phase@default map → map G2 phase@default map