Protein WEE1 map

Identifiers
WEE1 homolog (S. pombe)
HUGO:WEE1 HGNC:12761 ENTREZ:7465 UNIPROT:P30291 GENECARDS:WEE1 REACTOME:104871 KEGG:7465 ATLASONC:GC_WEE1 WIKI:WEE1

Maps_Modules
 dnarepair  map
 dnarepair  map
 dnarepair  map
 cellcycle  map

References
PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786

WEE1|​CHEK1site_pho@Nucleus

References
d_re603( dnarepair  map ):
In response to DNA damage, CHEK1 phosphorylates and activates WEE1, blocks cell cycle and allows DNA repair
PMID:23897299, PMID:23508805
d_re273:( dnarepair  map ) Wee1 phosphorylation of CDC2 keeps the complex inactive

WEE1@Nucleus

References
d_re603( dnarepair  map ):
In response to DNA damage, CHEK1 phosphorylates and activates WEE1, blocks cell cycle and allows DNA repair
PMID:23897299, PMID:23508805

Modifications:
In compartment: Nucleus
  1. WEE1@Nucleus map
  2. WEE1|​CHEK1site_pho@Nucleus map
In compartment: default
  1. WEE1|​pho@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. WEE1|​CHEK1site_pho@Nucleus map → map WEE1|​pho@default map
    2. WEE1|​pho@default map → map degraded
    3. WEE1@Nucleus map → map WEE1|​CHEK1site_pho@Nucleus map
    As Catalyser:
    1. CDK1:​CyclinB1*@default map → map CDK1|​Y14/15_pho:​CyclinB1*@default map
    2. CDK2:​CyclinE*@default map → map CDK2|​Y14/15_pho:​CyclinE*@default map
    3. CDK4_6*:​CyclinD*@default map → map CDK4_6*|​Y14_pho:​CyclinD*@default map
    4. CDK2:​CyclinA1*@default map → map CDK2|​Y14/15_pho:​CyclinA1*@default map
    5. CDK1:​CyclinA1*@default map → map CDK1|​Y14/15_pho:​CyclinA1*@default map